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The activity of this pathway in the liver is markedly impaired or absent in the fetus and newborn infant, in cirrhotic patients, and in patients with homocystinemia (Mato et al., 1994)

Gene duplication and evolution dynamics in the homeologous regions harbouring multiple prolamin and disease resistance gene families in hexaploidy wheat

A.ShiL.KawamuraI.OkitsuT.WadaA.et al (2013)

It should be emphasized that this effect does not necessarily mean that Asp itself is a pro-inflammatory factor, but more likely reflects its position in the coupling of energy metabolism and metabolic signaling: when shuttle activity and anabolic demand increase, Asp supply may become one of the limiting factors supporting pro-inflammatory transcription and effector molecule synthesis